Sumner Group Publications

Dobritsa, A. A., Nishikawa, S - I., Preuss, D., Urbanczyk-Wochniak, E., Sumner, L. W., Hammond, A., Carlson, A. L., & Swanson, R. J. (2009). LAP3, a novel plant protein required for pollen development, is essential for proper exine formation. Sexual Plant Reproduction, 22 (3), 167-177 doi: 10.1007/s00497-009-0101-8.

Pang, Y., Wenger, J., Saathoff, K., Peel, G. J., Wen, J. Q., Huhman, D. V., Allen, S. N., Tang, Y., Cheng, X., Tadege, M., Ratet, P., Mysore, K. S., Sumner, L. W., Marks, M. D., & Dixon, R. A. (2009). A WD40 repeat protein from Medicago truncatula is necessary for tissue-specific anthocyanin and proanthocyanidin biosynthesis, but not for trichome development. Plant Physiology, , DOI:10.1104/pp.109.144022 .

Farag, M. A., Deavours, B., de Fatima, A., Naoumkina, M., Dixon, R. A., & Sumner, L. W. (2009). Integrated metabolite and transcript profiling identify a biosynthetic mechanism for hispidol in Medicago truncatula cell cultures. Plant Physiology, DOI:10.1104/pp.109.141481.

Sawasdipuksa, N., Sumner, L. W., Lei, Z., & Sangvanich, P. (2009). Proteome analysis of Pithecellobium dulce seeds using two-dimensional gel electrophoresis and tandem mass spectrometry . Journal of the Science of Food and Agriculture, 89 (8), 1284-1291.

Tian, L., Peel, G. J., Lei, Z., Aziz, N., Dai, X., He, J., Watson, B. S., Zhao, P. X., Sumner, L. W., & Dixon, R. A. (2009). Transcript and proteomic analysis of developing white lupin (Lupinus albus L.) roots. BMC Bioinformatics, 9, 1 DOI:10.1186/1471-2229-9-1.

De-la-Pena, C., Lei, Z., Watson, B. S., Sumner, L. W., & Vivanco, J. M. (2008). Root-microbe communication through protein secretion. Journal of Biological Chemistry, 283 (37), 25247-25255 DOI:10.1074/jbc.M801967200.

Xu, P., Chen, F., Mannas, J. P. , Feldman, T., Sumner, L. W., & Roossinck, M. J. (2008). Virus infection improves drought tolerance. New Phytologist, 180 (4), 911-921.

Bedair, M., & Sumner, L. W. (2008). Current and emerging mass-spectrometry technologies for metabolomics. Trends in Analytical Chemistry, 27 (3), 238-250 DOI:10.1016/j.trac.2008.01.006 .

Kaimoyo, E., Farag, M. A., Sumner, L. W., Wasmann, C., Cuello, J. L., & VanEtten, H. D. (2008). Sub-lethal Levels of electric current elicit the biosynthesis of plant secondary metabolites. Biotechnology Progress, 24 (2), 377-384.

Badri, D. V., Loyola-Vargas, V. M., Broeckling, C. D., De-la-Pena, C., Jasinski, M., Santelia, D., Martinoia, E., Sumner, L. W., Banta, L. M., Stermitz, F., & Vivanco, J. (2008). Altered profile of secondary metabolites in the root exudates of Arabidopsis ATP-binding cassette transporter mutants. Plant Physiology, 146 (2), 762-771 DOI:10.1104/pp.107.109587.

Farag, M. A., Huhman, D. V., Dixon, R. A., & Sumner, L. W. (2008). Metabolomics reveals novel pathways and differential mechanistic and elicitor-specific responses in phenylpropanoid and isoflavonoid biosynthesis in Medicago truncatula cell cultures. Plant Physiology, 146 (2), 387-402.

Fiehn, O., Sumner, L. W., Rhee, S. Y. , Ward, J., Lange, B. M. , Lane, G., Roessner, U., Last, R., & Nikolau, B. J. (2007). Minimum reporting standards for plant biology context information in metabolomic studies. Metabolomics, 3 (3), 195-201.

Whaley, W. L., Rummel, J. D., Zemenu, E., Li, W., Yang, P., Rodgers, B., Bailey, J., Moody, J., Huhman, D. V., Maier, C., Sumner, L. W., & Starnes, S. D. (2007). Isolation and characterization of osajin and pomiferin: Discovery laboratory exercises for organic chemistry,. Chemical Educator, 12 (3), 179-184 DOI 10.1333/s00897072030a.

Naoumkina, M., Farag, M. A., Sumner, L. W., Tang, Y., Liu, C.-J., & Dixon, R. A. (2007). Different mechanisms for phytoalexin induction by pathogen and wound signals in Medicago truncatula. PNAS (Proceedings of the National Academy of Sciences), 104 (46), 17909-17915.

Zhang, J - Y., Broeckling, C. D., Sumner, L. W., & Wang, Z - Y. (2007). Heterologous expression of two Medicago truncatula putative ERF transcription factor genes, WXP1 and WXP2, in Arabidopsis led to increased leaf wax accumulation and improved drought tolerance, but differential response in freezing tolerance. Plant Molecular Biology, 64 (3), 265-278.

Urbanczyk-Wochniak, E., & Sumner, L. W. (2007). MedicCyc: A biochemical pathway database for Medicago truncatula. Bioinformatics, 23 (11), 1418-1423.

Sansone, S. A., Fan, T., Goodacre, R., Griffin, J. L., Hardy, N., Kaddurah-Daouk, R., Kristal, B., Lindon, J., Mendes, P. J., Morrison, N., Nikoau, B., Robertson, D., Sumner, L. W., Taylor, C., van der Werf, M., & Fiehn, O. (2007). The metabolomics standards initiative. Nature Biotechnology, 25 (8), 846-848.

Farag, M. A., Huhman, D. V., Lei, Z., & Sumner, L. W. (2007). Metabolic profiling and systematic identification of flavonoids and isoflavonoids in roots and cell suspension cultures of Medicago truncatula using HPLC-UV-ESI-MS and GC-MS. Phytochemistry, 68 (3), 342-354 DOI:10.1016/j.phytochem.2006.10.023.

Williams, B. J. , Cameron, C. J., Workman, R., Broeckling, C. D., Sumner, L. W., & Smith, J. T. (2006). Amino acid profiling in plant cell cultures: An inter-laboratory comparison of CE-MS and GC-MS. Electrophorsis, 28, 1371-1379.

Sumner, L. W., Shahandeh, H, Bouton, J. H., & Hammel, J. (2006). Amelioration of an acid soil profile through deep liming and surface application of gypsum. Soil Science, 50 (55), 1254-1258.

Zhou, L., Hopkins, A. A., Huhman, D. V., & Sumner, L. W. (2006). Efficient and sensitive method for quantitative analysis of alkaloids in hardinggrass (Phalaris aquatica L.). Journal of Agricultural and Food Chemistry, 54 (25), 9287-9291.

Deavours, B., Liu, C.-J., Naoumkina, M., Tang, Y., Farag, M. A., Sumner, L. W., Noel, J. P., & Dixon, R. A. (2006). Functional analysis of members of the isoflavone and isoflavanone O-methyltransferase enzyme families from the model legume Medicago truncatula. Plant Molecular Biology, 62 (4-5), 715-733 DOI 10.1007/s11103-006-9050-x .

Fiehn, O., Kristal, B., van Ommen, B., Sumner, L. W., Sansone, S. A., Taylor, C., & Kaddurah-Daouk, R. (2006). Establishing reporting standards for metabolomic and metabonomic studies: A call for participation. Omics, 10 (2), 158-163.

Farag, M. A., Ryu, C-M., Sumner, L. W., & Pare, P. W. (2006). GC-MS SPME profiling of rhizobacterial volatiles reveals prospective inducers of growth promotion and induced systemic resistance in plants. Phytochemistry, 67 (20), 2262-2268.

Broeckling, C. D., Reddy, I. R., Duran, A. L., Zhao, P. X., & Sumner, L. W. (2006). MET-IDEA: Data extraction tool for mass spectrometry-based metabolomics. Analytical Chemistry, 78, 4334-4341.

Zhang, J - Y., Broeckling, C. D., Blancaflor, E. B. , Sledge, M. K., Sumner, L. W., & Wang, Z - Y. (2005). Overexpression of WXP1, a putative Medicago truncatula AP2 domain-containing transcription factor gene, increases cuticular wax accumulation and enhances drought tolerance in transgenic alfalfa (Medicago truncatula). Plant Journal, 42 (5), 689-707 DOI:10.1111/j.1365-313X.2005.02405.x.

Tarpley, L., Duran, A. L., Kebrom, T. H., & Sumner, L. W. (2005). Biomarker metabolites capturing the metabolite variance present in a rice plant developmental period. Plant Biology, 5 (8), DOI:10.1186/1471-2229-5-8.

Lei, Z., Elmer, A. M., Watson, B. S., Dixon, R. A., Mendes, P. J., & Sumner, L. W. (2005). A two-dimensional electrophoresis proteomic reference map and systematic identification of 1367 proteins from a cell suspension culture of the model legume Medicago truncatula. Molecular and Cellular Proteomics, 4 (11), 1812-1825 DOI:10.1074/mcp.D500005-MCP200.

Frydman, A., Weisshaus, O., Huhman, D. V., Sumner, L. W., Bar-Peled, M., Lewinsohn, E., & Flurh, R. (2005). Metabolic engineering of plant cells for biotransformation of hesperedin into neohesperidin, a substrate for production of the low-calorie sweetener and flavor enhancer NHDC. Journal of Agricultural and Food Chemistry, 53 (25), 9708-9712.

Broeckling, C. D., Huhman, D. V., Farag, M. A., Smith, J. T., May, G. D., Mendes, P. J., Dixon, R. A., & Sumner, L. W. (2005). Metabolic profiling of Medicago truncatula cell cultures reveals the effects of biotic and abiotic elicitors on metabolism. Journal of Experimental Botany, 56 (410), 323-336 DOI:10.1093/jxb/eri058 .

Huhman, D. V., Berhow, M. A., & Sumner, L. W. (2005). Quantification of saponins in aerial and subterranean tissues of Medicago truncatuala. Journal of Agricultural and Food Chemistry, 53 (6), 1914-1920.

Achnine, L., Huhman, D. V., Farag, M. A., Sumner, L. W., Blount, J. W., & Dixon, R. A. (2005). Genomics-based selection and functional characterization of triterpene glycosyltransferases from the model legume . Plant Journal, 41 (6), 875-887.

Suzuki, H., Reddy, M .S. , Naoumkina, M., Aziz, N., May, G. D., Huhman, D. V., Sumner, L. W., Blount, J. W., Mendes, P. J., & Dixon, R. A. (2005). Methyl jasmonate and yeast elicitor induce differential transcriptional and metabolic re-programming in cell suspension cultures of the model legume Medicago truncatula. Planta, 220 (5), 696-707 DOI:10.1007/s00425-004-1387-2 /.

Sumner, L. W. (2004). Opinion: Potential of Metabolomis as a functional genomics tool. Trends in Plant Science, 9 (9), 418-425.

Hensley, K., Mou, S., Pye, Q., Dixon, R. A., Sumner, L. W., & Floyd, R. D. (2004). Chemical versus pharmacological actions of nutraceutical phytochemicals: antioxidant and anti inflammatory modalities. Journal of Nutraceutical Research, 2 (1), 13-26.

Jenkins, H., Hardy, N., Beckmann, M., Draper, J., Smith, J. T., Taylor, J. M., Fiehn, O., Goodacre, R., Bino, R. J., Hall, R. D., Kopka, J., Lange, B. M. , Lui, J. R., Mendes, P. J., Nikolau, B. J., Oliver, S. G., Paton, N., Roessner-Tunali, U., Saito, K., Smedsgaard, J., Sumner, L. W., Wurtele, E. S., & Kell, D. B. (2004). A proposed framework for the description of plant metabolomics experiments and their results. Nature Biotechnology, 22 (12), 1601-1606.

Frydman, A., Weisshaus, O., Bar-Peled, M., Huhman, D. V., Sumner, L. W., Marin, F. R., Lewinsohn, E., Flurh, R., Gressel, J., & Eyal, Y. (2004). Citrus fruit bitter flavors: isolation and the functional characterization of the gene Cm1,2RhaT encoding a 1,2 rhamnosyltransferase, a key enzyme of the biosynthesis of the bitter flavonoids of citru. Plant Journal, 40 (1), 88-100.

Bino, R. J., Hall, R. D., Fiehn, O., Kopka, J., Saito, K., Draper, J., Nikolau, B. J., Mendes, P. J., Roessner-Tunali, U., Beale, M. H., Lange, B. M. , Wurtele, E. S., & Sumner, L. W. (2004). Potential of metabolomics as a functional genomics tool. Trends in Plant Science, 19, 418-425.

Anand, A., Lei, Z., Sumner, L. W., Mysore, K. S., Arakane, Y., Bockus, W. W., & Muthukrishnan, S. (2004). Apoplastic extracts from a transgenic wheat line exhibiting lesion-mimic phenotype have multiple pathogenesis-related proteins that are antifungal. Molecular Plant-Microbe Interactions, 17 (12), 1306-1317 DOI:10.1094/MPMI.2004.17.12.1306.

Watson, B. S., Lei, Z., Dixon, R. A., & Sumner, L. W. (2004). Proteomics of Medicago sativa cell walls. Phytochemistry, 65 (12), 1709-1720 DOI:10.1016/j.phytochem.2004.04.026.

Noel, J. P., Dixon, R. A., Pichersky, E., Zubieta, C., & Sumner, L. W. (2003). Structural, functional, and evolutionary basis for methylation of plant small molecules. Recent Advances in Phytochemistry, 37, 37-58.

Sumner, L. W., Mendes, P. J., & Dixon, R. A. (2003). Plant Metabolomics: Large-scale phytochemistry in the functional genomics era. Phytochemistry, 62 (6), 817-836.

Watson, B. S., Asirvatham, V. S. , Wang, L - J., & Sumner, L. W. (2003). Mapping the proteome of Barrel Medic (Medicago truncatula). Plant Physiology, 131 (3), 1004-1123.

Dixon, R. A., & Sumner, L. W. (2003). Legume natural products: Understanding and manipulating complex pathways for human and animal health. Plant Physiology, 131 (March), 878-885.

Duran, A. L., Yang, J., Wang, L - J., & Sumner, L. W. (2003). Metabolomics spectral formatting, alignment and conversion tools. (MSFACTs). Bioinformatics, 19 (17), 2283-2293.

Liu, C.-J., Huhman, D. V., Sumner, L. W., & Dixon, R. A. (2003). Regiospecific hydroxylation of isoflavones by cythchrome P450 81E enzymes from Medicago truncatula. Plant Journal, 36 (4), 471-484.

Chen, F., Duran, A. L., Blount, J. W., Sumner, L. W., & Dixon, R. A. (2003). Profiling phenolic metabolites in transgenic alfalfa modified in lignin biosynthesis. Phytochemistry, 64, 1013-1021.

Hall, R. D., Beale, M. H., Fiehn, O., Hardy, N., Sumner, L. W., & Bino, R. J. (2002). Plant metabolomics; The missing link in functional genomics strategies. Plant Cell, 14, 1437-1440.

Sumner, L. W., Wolf-Sumner, B., White, S., & Asirvatham, V. S. (2002). Silver stain removal using H2o2 for enhancing peptide mass mapping by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Rapid Communications in Mass Spectrometry, 16 (3), 160-168.

Huhman, D. V., & Sumner, L. W. (2002). Metabolic profiling of saponins in Medicago sativa and Medicago truncatula using Hplc coupled to an electrospray ion-trap mass. Phytochemistry, 59, 347-360.

Blount, J. W., Masoud, S. A., Sumner, L. W., Huhman, D. V., & Dixon, R. A. (2002). Over-expression of cinnamate 4-hydroxylase leads to increased accumulation of acetosyringone in elicited tobacco cell-suspension cultures. Planta, 214 (6), 902-910.

Asirvatham, V. S. , Watson, B. S., & Sumner, L. W. (2002). Analytical and biological variances associated with proteomic studies of Medicago truncatula by two-dimensional polyacrylamide gel electrophoresis. Proteomics, 2 (8), 960-968.

Sumner, L. W. (1998). Definition of the redox states of cobalt-precorrinoids: Investigation of the substrate and redox specificity of CbiL from Salmonella typhimurium. Biochemistry, 37, 14917-14927 DOI:10.1021/bi981366f .

Sumner, L. W., Paiva, N. L., Dixon, R. A., & Geno, P. W. (1996). High-performance liquid chromatography/continuous-flow liquid secondary ion mass spectrometry of flavonoid glucosides in leguminous plant extracts. Journal of Mass Spectrometry, 31 (5), 472-485.

Orr, J., Sumner, L. W., Edwards, R., & Dixon, R. A. (1993). Determinations of cinnamic acid and 4-coumaric acid in alfalfa (Medicago sativa L.) cell suspension cultures using gas chromatography. Phytochemical Analysis, 4, 124.

Orr, J. D., Sumner, L. W., Edwards, R., & Dixon, R. A. (1993). Determination of cinnamic acid and 4-coumaric acid in alfalfa (Medicago Sativa L.) cell suspension cultures by gas chromatography. Phytochemical Analysis, 4, 124-130.

Freitas, M. A., Geno, P. W., Sumner, L. W., Cooks, M. E., Hudiburg, S. A., Ownby, C. L., Kaiser, A. D., & Odell, G. V. (1992). Citrate,a major component in snake venom. Toxicon, 30, 461.