Assistant Professor Xiaoqiang Wang

Xiaoqiang Wang, Ph.D

Associate Professor

Noble Researcher since 2002

Ph.D., Protein Crystallography, 1993, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China

Using crystallography as the main experimental technique, the structural biology laboratory is studying enzymes and other biologically important plant proteins involved in natural product biosynthesis and other biological processes. By determining the three-dimensional structures of proteins and protein-ligand complexes, researchers are able to reveal the structural basis of protein function, the detailed interactions between proteins and their binding partners and the mechanisms of their actions. Wang's lab joins the effort in Medicago truncatula functional genomics by collaborating with colleagues at the Noble Foundation to study the proteins from M. truncatula.

Research Video

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Recent Publications

Morgan, R. L., Zhou, H., Lehto, E., Nguyen, N. , Bains, A. , Wang, X., & Ma, W. (2010). Catalytic domain of the diversified Pseudomonas syringae type III effector HopZ1 determines the allelic specificity in plant hosts. Molecular Microbiology, 76 (2), 437-455 DOI:10.1111/j.1365-2958.2010.07107.x .

Modolo, L. V. , Escamilla-Trevino , L. L. , Dixon, R. A., & Wang, X. (2009). Single amino acid mutations of Medicago glycosyltransferase UGT85H2 enhance activity and impart reversibility . FEBS Letters, 583 (12), 2131-2135, DOI:10.1016/j.febslet.2009.05.046.

Li, L., Chang, Z., Pan, Z., Fu, Z., & Wang, X. (2008). Modes of heme binding and substrate access for cytochrome P450 CYP74A revealed by crystal structures of allene oxide synthase. PNAS (Proceedings of the National Academy of Sciences), 105, 13883-13888 DOI:10.1073.pnas.0804099105.

Chang, Z., Li, L., Pan, Z., & Wang, X. (2008). Crystallization and preliminary X-ray analysis of allene oxide synthase, cytochrome P450CYP74A2, from Parthenium argentatum. Acta Crystallographica section F-Structural Biology and Crystallization Communications, 64 (Part 7), 668-670 DOI:10.1107/S1744309108017545.

Pan, H., Wang, Y., Zhang, Y., Zhou, T., Fang, C., Nan, P., Wang, X., Li, X., Wei, Y., & Chen, J. (2008). Phenylalanine ammonia lyase functions as a switch directly controlling the accumulation of calycosin and calycosin-7-O-beta-D-glucoside in Astragalus membranaceus var. mongholicus plants. Journal of Experimental Botany, 59 (11), 3027-3037 DOI:10.1093/jxb/ern152 .